3-苄基6-叔丁基3,6-二氮杂双环[3.2.0]庚烷-3,6-二羧酸酯

3-苄基6-叔丁基3,6-二氮杂双环[3.2.0]庚烷-3,6-二羧酸酯 - Names and Identifiers

Name	(1R,5S)-3-benzyl 6-tert-butyl 3,6-diazabicyclo[3.2.0]heptane-3,6-dicarboxylate
Synonyms	6-Boc-3-Cbz-3,6-diazabicyclo[3.2.0]heptane 3-benzyl 6-tert-butyl 3,6-diazabicyclo[3.2.0]heptane-3,6-dicarboxylate O3-Benzyl O6-tert-butyl 3,6-diazabicyclo[3.2.0]heptane-3,6-dicarboxylate (1R,5S)-3-benzyl 6-tert-butyl 3,6-diazabicyclo[3.2.0]heptane-3,6-dicarboxylate 3,6-Diazabicyclo[3.2.0]heptane-3,6-dicarboxylic acid, 6-(1,1-dimethylethyl) 3-(phenylmethyl) ester
CAS	370880-79-8

3-苄基6-叔丁基3,6-二氮杂双环[3.2.0]庚烷-3,6-二羧酸酯 - Physico-chemical Properties

Molecular Formula	C18H24N2O4
Molar Mass	332.39416
Density	1.218±0.06 g/cm3(Predicted)
Boling Point	446.5±28.0 °C(Predicted)
pKa	-0.84±0.20(Predicted)
Storage Condition	2-8℃

3-苄基6-叔丁基3,6-二氮杂双环[3.2.0]庚烷-3,6-二羧酸酯 - Upstream Downstream Industry

Downstream Products

6-BOC-3,6-DIAZABICYCLO[3.2.0]HEPTANE

3-苄基6-叔丁基3,6-二氮杂双环[3.2.0]庚烷-3,6-二羧酸酯 - Introduction

(1R,5S)-3-benzyl 6-tert-butyl 3,6-diazabicyclo[3.2.0]heptane-3,6-dicarboxylate, also known as (1R,5S)-(1R,5S)-3-benzene 6-tert-butyl 3,6-diazabicyclo[3.2.0]heptane-3,6-dicarboxylate, is an organic compound. The following describes its nature, use, preparation and safety information:

Nature:
This compound is a colorless to pale yellow solid with a melting point of about 140-145 degrees Celsius. It is stable at room temperature and soluble in some organic solvents, such as chloroform, methanol and dichloromethane.

Use:
This compound has a wide range of applications. It can be used as a pharmaceutical intermediate for the preparation of various pharmaceuticals, such as antibiotics, anticancer drugs, etc. In addition, it can also be used in organic synthesis and chemical industry.

Method:
A common preparation method is by adding a quaternary ammonium salt to 4-cyanobenzeneacetonitrile. In the preparation process, the quaternary ammonium salt is first reacted with cyanobenzeneacetonitrile, and the electrophilic alkyne is generated under the catalysis of alkali. Then the alkyne reacts with the nucleophile, and then through a series of reaction steps, the target product is finally obtained.

Safety Information:
When handling and using this compound, pay attention to safety. It may be irritating to the eyes, skin and respiratory system and may be potentially dangerous to health. Therefore, appropriate personal protective equipment such as laboratory gloves, protective glasses and laboratory suits should be used during operation. In addition, work should be done in a well-ventilated area to avoid inhaling or coming into contact with powders or vapors of the compound. If necessary, it is recommended to consult a chemical professional or refer to the relevant safety data sheet.

Last Update：2024-04-09 20:52:54